Skin restoration (Polynucleotide)
Polynucleotide regenerates skin cells from deep inside by delivering highly biocompatible DNA fragments to our body. It is a skin rejuvenating treatment made of biological molecules called polynucleotides (PN) to improve the biological condition of our damaged skin.
What Is Pn, Polynucleotide?
A PN molecule is a biopolymer made up of nucleotide monomers bonded together. Nucleotides are the basic structural units which make up DNA. The DNA extract is obtained from salmon, then fragmented into PNs.
- It is heat-resistant and safe, with high biocompatibility with no side effects
- It activates the self-regenerating power of the skin and normalises the condition inside the skin
- It improves skin elasticity by recovering the condition of the epidermis and dermis
- It fundamentally and naturally recovers skin damaged by severe environmental factors
Why Do You Need Polynucleotide?
- To activate the self-recovering power of the skin
- To improve density and the overall elasticity of the skin
- To keep skin young and healthy
And because damaged skin has less capability of self-regeneration, it may accelerate the process of ageing of the skin and increase the appearance of fine lines, often caused by the loss of skin elasticity.
Benefits Of Polynucleotide
Excellent Skin Restoration Effects
- Activates the self-regeneration ability of the skin to improve skin problems such as acne scars, inflammation, dark eye circles, stretch marks and wrinkles
Improvement of Skin Elasticity and Fine Lines
- Restores the Extra Cellular Matrix (ECM) of the skin to promote secretion of collagen to recover damaged skin caused by external stimulants
Recovery of Skin pH Balance
- Reduces sebum secretion and enlarged skin pores
- Improves skin tone and texture
How Frequently Do I Need To Get This Treatment?
Polynucleotide fundamentally regenerates and recovers damaged skin by activating the self-renewal ability of the skin. To see the full benefits of the treatment, it is recommended to have the treatment in 3 sessions with a 4-week interval in between.
Are There Any Side Effects And Downtime?
There are no known side effects, as polynucleotides are composed of DNA fragments highly biocompatible with our body. You may experience swelling on the treated spot on the day of the treatment which should go off within 1-2 days, enabling you to go back to your routine.
Reference
- L’EVOLUZIONE DELLA RICERCA NELLA BIORIVITALIZZAZIONE, 15TH world congress of Aesthetic Medicine, Rome Italy 5-9 May.2005
- Evaluation on Polynucleotide Effect on Skin Beauty, P&K, 2014
- Clinical Test for REJURAN, Seoul National University Bundang Hospital, 2014
- Long chain polynucleotides gel and skin biorevitalization, Journal of Plastic Dermatology, 2007
Polynucleotide
Doctor-run, HSA-compliant. We never recommend more than what is needed.

Dr Ivan Tan Khee Hon
MBBS (S'pore) · GDFP Dermatology (S'pore) · DP Dermatology (Wales) · MSc Non-surgical Facial Aesthetics (UK)
Every injection and procedure at Medical Aesthetics is performed by Dr Tan - 25 years of practice, official trainer for Allergan, Galderma, Teoxane, IBSA, Merz.
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